Journal vol.6 no.1 abstract4 of The Japan Health Care Dental Association

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The Journal of The Japan Health Care Dental Association

The Journal of The Japan Health Care Dental Association Vol.6 No.1, 2004
abstract

Reconsideration of Diagnosis, Treatment and Maintenance of Periodontal Disease

Shinya Murakami, DDS, PhD

Periodontitis is different from other infectious diseases, because it is an inflammatory disease with a unique feature of periodontopathic bacteria colonizing in the exterior portion of the soft tissues in many cases. The local host resistance and reaction to the bacteria triggers the expression of the disease. We evaluated mRNA levels of the cytokines, and our study indicates that with the increase in the severity of clinical findings the levels of the cytokines (IL-1Β IL-6, and TNFΑ), potent stimulator of bone resorption, maintain high in the local sites. In order to understand periodontitis, we need to have a better understanding of commonly called "Constitution" as well as bacteria. The interindividual difference of 1 codogenic (1 base) (more than 1% frequency of the population) is called as "polymorphism", and this codogenic difference prescribes ?the constitution?. Kornman et al demonstrated in their study that there is a correlation between IL-1 genotype and severity of periodontitis. About 30 % of the Caucasians and about 7-10% of the Japanese are IL-1 genotype positive group. Thus, there are controllable risk factors of periodontitis, such as plaque accumulation, and uncontrollable risk factors. We think that it will become more important to offer a patient a preventive program of periodontitis by objectively evaluating his/her risk factors. The purpose of this review is to describe the significance of the classification of periodontitis developed by AAP and a workflow of diagnosis and treatment of periodontitis within its scope, subject to the understanding of periodontitis.

J Health Care Dent. 2004; 6: 23-41.

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