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The Journal of The Japan Health Care Dental Association
The Journal of The Japan Health Care Dental Association Vol.7 No.1, 2005
abstract
Drug Utilization Review in Elderly People and Meaning of Information about Dry Mouth as Adverse Reaction
Mayumi Mochizuki, PhD
With the cooperation of 2,269 adult dental patients from 35 dental offices, survey was conducted on: what medicines the dental patients take, and what medicines may cause dry mouth.
Over sixty percent of elderly patients took medicines and about half of those medicines were reported dry mouth in their package insert.
Our data could not show that antipsychotics, antidepressants, and antimuscarinic drugs well known as causative drugs of dry mouth produced dry mouth, because the number of cases treated with these drugs were very small in our data. On the other hand, since cardiovascular drugs and H2 blockers were administered to many patients, patients treated with these drugs showed many cases having dry mouth. However, it should be kept in mind that most of medicines were co-adminstered with other 1 to 3 medicines, therefore we could not identify which medicine cause dry mouth. As many different medicines were found in this survey, it was quite difficult to analyse the relation between dry mouth by medicines and the amount of stimulative saliva.

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